ENMD-2076
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
934353-76-1
C07590-5mg
Aurora Kinase
Cell Cycle
CC1=CC (=NN1) NC2=CC (=NC (=N2) C=CC3=CC=CC=C3) N4CCN (CC4) C
C21H25N7
ENMD-2076 has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B and less potent to RET, SRC, NTRK1/TRKA, CSF1R/FMS, VEGFR2/KDR, FGFR and PDGFRα. ENMD-2076 inhibits the growth of a wide range of human solid tumor and hematopoietic cancer cell lines with IC50 from 0.025 to 0.7 μM, which induces apoptosis and G2/M phase arrest. Phase 2.
2 years -80 in solvent
Beschrijving
ENMD-2076 Beschikbaar in 5 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
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