ENO1 Antilichaam, KO gevalideerd

This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy.

2023

P06733

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-434 of human ENO1 (NP_001419.1) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Cancer, Signal Transduction, Transcription

Affinity purification

PC-3

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 47kDa

IgG

ENO1

Ramos

NCI-H460

HeLa

THP-1

Mouse kidney

Enolase 1, (alpha)

Homo sapiens

ENO1, NNE, PPH, MPB1, ENO1L1

WB, IF, IP

Liquid