ENOS (Ab 1177) Antilichaam

Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF) -induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.

4846

P29474

NP_000594.2

Human, Mouse, Rat

ENOS (Ab-1177) antibody was raised against a peptide sequence around aa.1175~1179 (T-Q-S-F-S) derived from Human eNOS.

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

140 kDa

This antibody detects endogenous level of total eNOS protein.

Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200

NOS3

Nitric oxide synthase 3 (endothelial cell)

Homo sapiens

Fulton, D. et al. (1999) Nature 399, 597-601. Harris, M. B. et al. (2001) J. Biol. Chem. 276, 16587-16591. Thomas, S. R. et al. (2002) J. Biol. Chem. 277, 6017-6024.

ENOS, ECNOS, Constitutive NOS, EC-NOS, NOS3, NOSIII

WB, IF

40254422

Liquid