ENOS (fosfo Thr494) Antilichaam

Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF) -induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.

4846

P29474

NP_000594.2

Human, Mouse, Rat

ENOS (phospho Thr494) antibody was raised against a peptide sequence around phosphorylation site of threonine 494 (R-K-K (p) -T-F derived from Human eNOS .

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

140 kDa

IgG

The antibody detects endogenous levels of eNOS only when phosphorylated at threonine 494.

Western Blot: 1:500~1:1000

NOS3

Nitric oxide synthase 3 (endothelial cell)

Homo sapiens

Janssens S.P., J. Biol. Chem. 267:14519-14522 (1992) .

Janssens S.P., J. Biol. Chem. 267:22694-22694 (1992) .

Marsden P.A., FEBS Lett. 307:287-293 (1992)

CNOS, EC-NOS, ECNOS, NOS, NOS3

WB

40254422

Liquid