ENOSF1 Polyklonale Antilichaam, APC-Cy5.5 Vervoeging

The rTS gene codes for a naturally occurring antisense RNA to thymidylate synthase (TS) mRNA and two proteins (rTSalpha and rTSbeta (also known as ENOSF1) ) . The role of the major protein product of rTS, ENOSF1 has been linked to alterations in TS protein expression, but the precise function of ENOSF1 is unknown. Expression of rTS is associated with growth arrest in cell culture, but its overexpression has been noted in cells resistant to anticancer drugs such as 5-fluorouracil and methotrexate. Studies have shown that increased expression of ENOSF1 is associated with the decrease in TS protein expression due to production of novel, diffusible signal molecules.

Enolase superfamily member 1; ENOSF 1; HSRTSBETA; RTS alpha; RTS; RTS beta; RTS beta protein; TYMSAS

Cytoplasm

351-443/443

ENOSF1

APC-Cy5.5

KLH conjugated synthetic peptide derived from human ENOSF1

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

650nm/694nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Human, Dog, Rabbit