Ent-Levobunolol (hydrochloride)

Ent-Levobunolol ((R) -Bunolol) hydrochloride is a competitive β-adrenergic receptor blocker. ent-Levobunolol hydrochloride inhibits the transmission of sympathetic nerve impulses, reduces the production of aqueous humor, and constricts blood vessels in the eye, thereby reducing intraocular pressure. ent-Levobunolol hydrochloride is promising for research of ocular hypertension diseases such as glaucoma[1].

27867-05-6

(R) -Bunolol (hydrochloride)

12352005

Adrenergic Receptor

GPCR/G Protein; Neuronal Signaling

Neuroscience-Neuromodulation

Cardiovascular Disease

O=C1CCCC2=C1C=CC=C2OC[C@H](O)CNC(C)(C)C.Cl

C17H26ClNO3

327.85

[1]Patlolla RR, et al. Lipase mediated new chemo-enzymatic synthesis of (RS) -, (R) -, and (S) -bunolol. Chirality. 2024 Jan;36 (1) :e23627.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-B1035C/

Reference compound1

No Development Reported

β adrenergic receptor