Eotaxine-antilichaam

Eotaxin Antibody: Chemokines play a key role in inflammation. The CC chemokine eotaxin is a potent and specific eosinophil chemoattractant that is expressed by a variety of cell types in certain inflammatory conditions. Some G-protein coupled chemokine receptors are also utilized as virus coreceptors for fusion and infection of cells. The eotaxin receptor CCR3 is required for HIV-1 entry into target cells such as microglia and eotaxin inhibits the infection of HIV-1.

6356

P51671

CAB07027

Human

Unconjugated

Primary Antibodies

Chemokines & Cytokines, Infectious Disease

Eotaxin Antibody is affinity chromatography purified via peptide column.

Cat. No. 1201 - HeLa Cell Lysate

1 mg/ml

Predicted species reactivity based on immunogen sequence: Pig: (80%)

Eotaxin Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

Eotaxin antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

9 - 18 kDa

IgG

CCL11

Cat. No. 17-010 - HEK293 Cell Slide

Chemokine (C-C motif) ligand 11

Homo sapiens

Kitaura M, Nakajima T, Imai T, et al. Molecular cloning of human eotaxin, an eosinophil-selective CC chemokine, and identification of a specific eosinophil eotaxin receptor, CC chemokine receptor 3. J Biol Chem 1996;271:7725-30

Ponath PD, Qin S, Ringler DJ, et al. Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils. J Clin Invest 1996;97:604-12

He J, Chen Y, Farzan M, et al. CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia. Nature. 1997;385 (6617) :645-9

Choe H, Farzan M, Sun Y, et al. The β -chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell. 1996;85:1135-48 (WD0500)

Eotaxin Antibody: SCYA11, SCYA11, Eotaxin, C-C motif chemokine 11

ELISA, WB, ICC, IF

2462478

Liquid