EPB41 (fosfo Tyr660/418) Antilichaam

Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4.1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.

2035

P11171

NP_001159477.1

Human, Mouse

EPB41 (phospho Tyr660/418) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 660/418 (N-I-Y (p) -I-R) derived from Human EPB41.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

60 kDa

IgG

The antibody detects endogenous levels of EPB41 only when phosphorylated at tyrosine 660/418.

Western Blot: 1:500~1:1000

EPB41

Erythrocyte membrane protein band 4.1

Homo sapiens

Conboy J.G., Proc. Natl. Acad. Sci. U.S.A. 83:9512-9516 (1986) .

Tang T.K., Adv. Exp. Med. Biol. 241:81-95 (1988) .

Tang T.K., Proc. Natl. Acad. Sci. U.S.A. 85:3713-3717 (1988) .

E41P, EPB4.1, band 4.1, P4.1

WB

260436831

Liquid