EphA1 Antilichaam [5D2A4 / 5D2A10]

EPH receptor A1 (EphA1), with 976-amino acid protein (about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date and their ligands, the ephrins, can be subdivided into two major subclasses, ephrin-A and ephrin-B. Interaction of Eph receptor tyrosine kinases with their membrane bound ephrin ligands initiates bidirectional signaling events that regulate cell migratory and adhesive behavior, particularly in the nervous system. They have been implicated in various developmental processes, including axonal guidance, angiogenesis, morphogenesis and carcinogenesis.

2041

P21709

NP_005223.4

Human

Ni-NTA purified truncated recombinant EphA1 expressed in E. Coli strain BL21 (DE3) .

5D2A4 / 5D2A10

Unconjugated

Primary Antibodies

Neuroscience, Growth Factors

Antibody is purified by protein A affinity chromatography.

Batch dependent

Purified antibody in PBS containing 0.03% sodium azide.

None

Blue Ice

EphA1 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG1

EPHA1

EPH receptor A1

Homo sapiens

Shannon L. Duffy, Kirsten A. Steiner, Patrick P.L. Tam Gene Expr Patterns. 2006 Feb 6.

Elena B. Pasquale. Nat Rev Mol Cell Biol.2005 Jun; 6 (6) : 462-75.

EPH, EPHT, EPHT1

WB, IHC

221316650