EPHA3/4/5 (fosfo-Tyr779/833) Antilichaam

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands.

2042;2043

P29320;54764;54756

NP_004429.1

Human, Mouse, Rat

EPHA3/4/5 (phospho Tyr779/833) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 779/833 (E-A-Y (p) -T-T) / (Q-D-V (p) -I-K) derived from Human EPHA3/4/5.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

110 kDa

IgG

The antibody detects endogenous levels of EPHA3/4/5 only when phosphorylated at tyrosine 779/833.

EPHA3, EPHA4

EPH receptor A3, EPH receptor A4

Homo sapiens

Wicks I.P., Proc. Natl. Acad. Sci. U.S.A. 89:1611-1615 (1992) .

Chiari R., Cancer Res. 60:4855-4863 (2000) .

Boyd A.W., J. Biol. Chem. 267:3262-3267 (1992) .

EPA3, ETK, HEK, MEK4, REK

IHC

21361241

Liquid