Ephrine B2 (fosfo Tyr316) Antilichaam

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.

1948

P52799

NP_004084.1

Human, Mouse

Ephrin-B2 (Phospho-Tyr316) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 316 (P-V-Y (p) -I-V) derived from Human Ephrin-B2.

Unconjugated

Primary Antibodies

Phospho-Specific, Apoptosis, Cancer, Cell Cycle

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

37 kDa

This antibody detects endogenous levels of Ephrin-B2 only when phosphorylated at tyrosine 316.

Western Blot: 1:500~1:1000

EFNB2

Ephrin-B2

Homo sapiens

Chrencik JE, et al. (2006) J Biol Chem;281 (38) : 28185-28192. Kertesz N, et al. (2006) Blood;107 (6) : 2330-2338. Noren NK, et al. (2004) Proc Natl Acad Sci USA;101 (15) : 5583-5588

HTKL, EPLG5, Htk-L, LERK5, MEK1, PRKMK1, HTKL

WB

4758250

Liquid