Ephrine B2 (fosfo-Tyr330) Antilichaam

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma) . Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca (2+) /calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.

1948

P52799

NP_004084.1

Human, Mouse

Ephrin-B2 (Phospho-Tyr330) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 330 (N-I-Y (p) -Y-K) derived from Human Ephrin-B2.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

37 kDa

This antibody detects endogenous levels of Ephrin-B2 only when phosphorylated at tyrosine 330.

Western Blot: 1:500~1:1000

EFNB2

Ephrin-B2

Homo sapiens

Chrencik JE, et al. (2006) J Biol Chem;281 (38) : 28185-28192. Kertesz N, et al. (2006) Blood; 107 (6) : 2330-2338. Noren NK, et al. (2004) Proc Natl Acad Sci USA; 101 (15) : 5583-5588.

HTKL, EPLG5, Htk-L, LERK5, NR1C3, HTKL, MGC126226

WB

4758250

Liquid