Epi-D-Captopril
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Epi-D-Captopril (epi-D-SQ 14225) is a stereoisomer of Captopril and an inhibitor of metallo-β-lactamases (MBLs). The IC50 values of epi-D-Captopril against NDM-1, IMP-1, and VIM-2 are 64 μM, 173 μM, and 5.5 μM, respectively. epi-D-Captopril is expected to be used in the research of diseases caused by MBLs-related drug-resistant bacterial infections[1].
112243-88-6
Epi-D-SQ 14225
12352005
Beta-lactamase
Anti-infection
COVID-19-immunoregulation
Infection
SC[C@H](C)C(N1[C@H](CCC1)C(O)=O)=O
C9H15NO3S
217.29
[1]Brem J, et al. Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers. Antimicrob Agents Chemother. 2015 Oct 19;60 (1) :142-50.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-B0368C/
Reference compound1
No Development Reported
Beschrijving
Epi-D-Captopril (epi-D-SQ 14225) is a stereoisomer of Captopril and an inhibitor of metallo-β-lactamases (MBLs). The IC50 values of epi-D-Captopril against NDM-
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