Epibetulinezuur-d3

Epibetulinic acid-d3 is the deuterium labeled Epibetulinic acid. Epibetulinic acid exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity[1].

12352211

Isotope-Labeled Compounds; NO Synthase; Prostaglandin Receptor

GPCR/G Protein; Immunology/Inflammation; Others

Inflammation/Immunology

[H][C@]12[C@](C)([C@@]3(CC[C@]4(C(C)([C@@]([2H])(C([2H])(C[C@@]4([C@]3(CC2)[H])C)[2H])O)C)[H])C)CC[C@@]5([C@@]1([C@@H](CC5)C(C)=C)[H])C(O)=O

C30H45D3O3

459.72

[1]Reyes CP, et al. Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2. Bioorg Med Chem. 2006 Mar 1;14 (5) :1573-9.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W746847/

Isotope-Labeled Compounds

No Development Reported