EPOR Polyklonale Antilichaam, PE-Cy5 Vervoeging

Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.

EPO-R; Erythropoietin receptor; EPOR

2057

P19235

Secreted, Cell membrane, Extracellular matrix

Human, Rat

301-450/508

EPOR

PE-Cy5

KLH conjugated synthetic peptide derived from human EPOR

WB

Purified by Protein A.

488nm/670nm

1µg/µl

WB (1:300-5000)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

2057

Mouse, Dog, Cow, Horse