Epoxychinomicine C

Epoxyquinomicin C is an antibiotic that can be isolated from Amycolatopsis sp. Epoxyquinomicin C exhibits anti-inflammatory effects against collagen-induced arthritis. Epoxyquinomicin C can be designed for synthesis of the NF-κB Inhibitor DHMEQ[1][2].

200496-85-1

12352005

Antibiotic

Anti-infection

Infection; Inflammation/Immunology

OC[C@]12[C@]([C@H](C(NC(C3=C(C=CC=C3)O)=O)=CC2=O)O)([H])O1

C14H13NO6

291.26

[1]Matsumoto N, et al., Epoxyquinomicins A, B, C and D, new antibiotics from Amycolatopsis. I. Taxonomy, fermentation, isolation and antimicrobial activities. J Antibiot (Tokyo) . 1997 Nov;50 (11) :900-5.|[2]Lin Y, et al., Inhibition of Late and Early Phases of Cancer Metastasis by the NF-κB Inhibitor DHMEQ Derived from Microbial Bioactive Metabolite Epoxyquinomicin: A Review. Int J Mol Sci. 2018 Mar 3;19 (3) :729.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N14977/

Natural Products

No Development Reported