
EPR1 Polyklonale Antilichaam, Biotinevervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Cellular receptors for blood proteases regulate chemotaxis, extracellular proteolysis, and growth behavior of normal and malignant cells. Effector cell protease receptor-1 (EPR1) is a receptor for the coagulation protease factor Xa. EPR1 is characterized by a cysteine-rich extracellular module, a single membrane-spanning domain, and a serine-rich cytoplasmic tail featuring at least 15 potential phosphorylation sites. EPR1 also contains 2 N-linked glycosylation sites, 4 O-linked glycosylation sites, and a chondroitin sulfate attachment site, which may provide anchoring for carbohydrate chains, EPR1 transfectants bind to factor Xa in a specific and saturable manner, and in the absence of factor V/Va promote prothrombin activation in a factor Xa concentration-dependent reaction. Activated platelets and megakaryocytes express EPR1. Both EPR1 and membrane-bound factor Va are thought to be required to mediate factor Xa binding to the activated platelet to form a functional prothrombinase complex.
Effector cell peptidase receptor 1; Effector cell protease receptor 1; EPR 1; EPR1; EPR-1.
8475
• Rabbit
Human
51-150/337
EPR1
• Polyclonal
• IgG
Biotin
KLH conjugated synthetic peptide derived from human EPR1
WB, IHC-P
Purified by Protein A.
1µg/µl
WB (1:300-5000), IHC-P (1:200-400)
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C for 12 months.
8475
Beschrijving
EPR1 Polyklonale Antilichaam, Biotinevervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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