EPS15 (fosfo-Tyr849) Antilichaam

This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

2060

P42566

NP_001972.1

Human, Mouse, Rat

EPS15 (phospho Tyr849) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 849 (S-A-Y (p) -P-S) derived from Human Ephrin EPS15.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

100 kDa

IgG

The antibody detects endogenous levels of EPS15 only when phosphorylated at tyrosine 849.

Western Blot: 1:500~1:1000

EPS15

Epidermal growth factor receptor pathway substrate 15

Homo sapiens

Wong W.T., Oncogene 9:1591-1597 (1994) .

Bernard O.A., Oncogene 9:1039-1045 (1994) .

AF1P, MLLT5, EPS15, Protein Eps15

WB

229577185

Liquid