ER ligand-8
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
ER ligand-8 is an ER (Estrogen Receptor/ERR) ligand that can be used to synthesize the PROTAC molecule ERD-1233.
2229713-97-5
12352005
Estrogen Receptor/ERR; Ligands for Target Protein for PROTAC
PROTAC; Vitamin D Related/Nuclear Receptor
Cancer
O=S(OC1=CC=C([C@H]2[C@@H](C3=CC=CC=C3)CCC4=C2C=CC(OC(C)(C)C)=C4)C=C1)(C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)=O
C30H27F9O4S
654.58
[1]Ranjan Kumar Acharyya, et al. Discovery of ERD-1233 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader for the Treatment of ER+ Human Breast Cancer. J Med Chem. 2024 Nov 14;67 (21) :19010-19037.
Room Temperature
-20°C, 3 years; 4°C, 2 years (Powder)
http://file.medchemexpress.com/batch_PDF/HY-201580/
Reference compound1
No Development Reported
Beschrijving
ER ligand-8 is an ER (Estrogen Receptor/ERR) ligand that can be used to synthesize the PROTAC molecule ERD-1233.
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