ERAB-antilichaam

Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD) .

3028

Q99714

NP_004484.1

Human, Mouse, Rat

ERAB antibody was raised against a peptide sequence around aa.253~257 (L-D-G-A-I) derived from Human ERAB.

Unconjugated

Primary Antibodies

Neuroscience

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

27 kDa

This antibody detects endogenous level of total ERAB protein.

Western Blot: 1:500~1:1000

HSD17B10

Hydroxysteroid (17-beta) dehydrogenase 10

Homo sapiens

Holzmann J., Frank P., Loeffler E., Bennett K. L., Gerner C., Rossmanith W. Cell 135:462-474 (2008)

ABAD, CAMR, ERAB, HCD2, MHBD, HADH2, MRPP2, MRX17, MRX31, SCHAD, MRXS10, SDR5C1, 17b-HSD10, DUPXp11.22, ABAD

WB

4758504

Liquid