
ERAP2 Proteïne, menselijk, recombinant (zijn)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Leukocyte-derived arginine aminopeptidase (LRAP), also known as endoplasmic reticulum-aminopeptidase 2 (ERAP2), is the second identified aminopeptidase localized in the in the lumenal side of endoplasmic reticulum (ER) processing antigenic peptides presented to major histocompatibility complex (MHC) class I molecules. It is a 96-amino acid protein with significant homology to placental leucine aminopeptidase and adipocyte-derived leucine aminopeptidase. LRAP preferentially hydrolyzes the basic residues Arg and Lys, and contains the HEXXH (X) 18E zinc-binding motif, which is the characteristic of the M1 family of zinc metallopeptidases which also includes PILS/ARTS1/ERAP1 and LNPEP/PLAP. Induced by interferon-gamma, LRAP is able to trim various MHC class I antigenic peptide precursors.
Ice Packs
-20°C
Beschrijving
ERAP2 Proteïne, menselijk, recombinant (zijn) Beschikbaar in 5 µg. Bestel eenvoudig online met snelle levering.
Specificaties
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