ERCC3 Antilichaam

This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.

2071

P19447

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 512-782 of human ERCC3 (NP_000113.1) .

Unconjugated

Primary Antibodies

Apoptosis, Cancer, Cell Cycle, Transcription

Affinity purification

Jurkat

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 89kDa

IgG

WB: 1:500 - 1:2000

ERCC3

Mouse kidney

Rat kidney

Excision repair cross-complementing rodent repair deficiency, complementation group 3

Homo sapiens

ERCC3, BTF2, GTF2H, RAD25, TFIIH p89, TFIIH, XPB, BTF2 p89, XPBC, TFIIH 89 kDa subunit

WB

Liquid