ERCC8 Mouse Monoclonal Antibody [Kloon ID: LBI1G2]

This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS) . CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014]

Carrier-free (BSA/glycerol-free) ERCC8 mouse monoclonal antibody, clone LBI1G2

CKN1; CSA; UVSS2

Homo sapiens ERCC excision repair 8, CSA ubiquitin ligase complex subunit (ERCC8), transcript variant 3, mRNA.

1161

Q13216

Unconjugated

Nucleotide excision repair, Ubiquitin mediated proteolysis

Nucleotide excision repair, Ubiquitin mediated proteolysis

WB 1:500, IHC 1:150

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Transcription Factors

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

ERCC8

https://www.ncbi.nlm.nih.gov/gene/?term=1161

https://www.uniprot.org/uniprot/Q13216