ERCC8 Polyklonale Antilichaam, HRP-vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX (ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair. It is required for the recruitment of XAB2, HMGN1 and TCEA1/TFIIS to a transcription-coupled repair complex which removes RNA polymerase II-blocking lesions from the transcribed strand of active genes.
CSA; CKN1; UVSS2; DNA excision repair protein ERCC-8; Cockayne syndrome WD repeat protein CSA; ERCC8
1161
Q13216
Nucleus
• Rabbit
Human, Mouse, Rat
161-260/396
ERCC8
• Polyclonal
• IgG
HRP
KLH conjugated synthetic peptide derived from human ERCC8/CSA
WB, ELISA, IHC-P, IHC-F
Purified by Protein A.
1µg/µl
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
1161
Horse
Beschrijving
ERCC8 Polyklonale Antilichaam, HRP-vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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