![ERG Mouse Monoclonal Antibody [Kloon ID: LBI5D10]](/_ipx/q_80/productPlaceholder.webp)
ERG Mouse Monoclonal Antibody [Kloon ID: LBI5D10]
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan
Carrier-free (BSA/glycerol-free) ERG mouse monoclonal antibody, clone LBI5D10
Erg-3; p55
Homo sapiens ETS transcription factor ERG (ERG), transcript variant 1, mRNA.
2078
P11308
Unconjugated
WB 1:200~4000, IF 1:100
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Druggable Genome, Transcription Factors
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
ERG
https://www.ncbi.nlm.nih.gov/gene/?term=2078
https://www.uniprot.org/uniprot/P11308
Beschrijving
ERG Mouse Monoclonal Antibody [Kloon ID: LBI5D10] Beschikbaar in 100 µg. Bestel eenvoudig online met snelle levering.
Specificaties
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