ERK1/2-remmer 12
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
ERK1/2 inhibitor 12 (compound 76.3) is a ERK1/2 inhibitor which inhibits ERK-mediated phosphorylation of caspase-9 and the p90Rsk-1 kinase. ERK1/2 inhibitor 12 exhibits anti-cancer activity and can be utilized in cancer research[1].
350509-85-2
12352005
H302-H315-H319-H335
ERK
MAPK/ERK Pathway; Stem Cell/Wnt
Cancer
O=C1S/C(C(N1CCN)=O)=C\C2=CC=C3OCOC3=C2
C13H12N2O4S
292.31
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
[1]Boston SR, et al. Characterization of ERK docking domain inhibitors that induce apoptosis by targeting Rsk-1 and caspase-9. BMC Cancer. 2011 Jan 10;11:7.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W838814/
Reference compound1
No Development Reported
Beschrijving
ERK1/2 inhibitor 12 (compound 76.3) is a ERK1/2 inhibitor which inhibits ERK-mediated phosphorylation of caspase-9 and the p90Rsk-1 kinase. ERK1/2 inhibitor 12
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