ERK5 (MAPK7) Mouse Monoclonal Antibody [Kloon ID: LBI5C7]

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5) . It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq]

Carrier-free (BSA/glycerol-free) MAPK7 mouse monoclonal antibody, clone LBI5C7

BMK1; ERK4; ERK5; PRKM7

Homo sapiens mitogen-activated protein kinase 7 (MAPK7), transcript variant 3, mRNA.

5598

Q13164

Unconjugated

Gap junction, GnRH signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway

Gap junction, GnRH signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway

WB 1:2000, IF 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Protein Kinase

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

MAPK7

https://www.ncbi.nlm.nih.gov/gene/?term=5598

https://www.uniprot.org/uniprot/Q13164