ERO1LB Polyklonale Antilichaam, PE-Cy5,5 Vervoeging

Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50% of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10%) . Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.

Endoplasmic oxidoreductin-1-like protein B; ERO1-L-beta; ERO1B; ERO1-like protein beta; Oxidoreductin-1-L-beta

56605

Q86YB8

Cytoplasm

Mouse

1-100/467

ERO1LB

PE-Cy5.5

KLH conjugated synthetic peptide derived from human ERO1LB

WB

Purified by Protein A.

488nm/694nm

1µg/µl

WB (1:300-5000)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

56605

Human, Rat, Rabbit, GuineaPig