ERRF Antilichaam

ERRF Antibody: The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.

149563

Q8NEQ6

NP_849162

Human, Mouse

Unconjugated

Primary Antibodies

Cancer, Cell Cycle

ERRF Antibody is affinity chromatography purified via peptide column.

Cat. No. 1201 - HeLa Cell Lysate

1 mg/mL

ERRF Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

ERRF antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

C1orf64

Cat. No. 1288 - A20 Cell Lysate

Cat. No. 17-001 - HeLa Cell Slide

Chromosome 1 open reading frame 64

Homo sapiens

Su D, Fu X, Fan S, et al. Role of ERRF, a novel ER-related nuclear factor, in the growth control of ER-positive human breast cancer cells. Am. J. Pathol. 2012; 180:1189-201.

ERRF Antibody: ERRF, Uncharacterized protein C1orf64

ELISA, WB, IHC-P, IF

30519894

Liquid