ERVFRD-1 Antilichaam

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.

405754

P60508

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 16-250 of human ERVFRD-1 (NP_997465.1) .

Unconjugated

Primary Antibodies

Other

Affinity purification

SH-SY5Y

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 38kDa

IgG

WB: 1:1000 - 1:4000

ERVFRD-1

HT-29

293T

A-549

K-562

22Rv1

Syncytin-2

Homo sapiens

Syncytin-2, Endogenous retrovirus group FRD member 1, Envelope polyprotein, HERV-FRD, HERV-FRD_6p241 provirus ancestral Env polyprotein, Surface protein, SU, Transmembrane protein, TM, ERVFRD-1, ERVFRDE1

WB

Liquid