(Erythro) 1′,2′-Dihydroxyasaron

(erythro) 1′,2′-Dihydroxyasarone is a metabolite of Beta-asarone and can also be isolated from the roots of Acorus tatarinowii. (erythro) 1′,2′-Dihydroxyasarone can form glucuronic acid conjugates in vivo and be excreted in urine. (erythro) 1′,2′-Dihydroxyasarone can serve as a marker for the metabolism and toxic risk assessment of Beta-asarone[1][2].

321365-68-8

12352005

Drug Metabolite

Metabolic Enzyme/Protease

Others

C[C@@H](O)[C@H](C1=C(C=C(C(OC)=C1)OC)OC)O

C12H18O5

242.27

[1]Hu J, et al. Phenylpropanes from Acorus tatarinowii. Planta Med. 2000 Oct;66 (7) :662-4.|[2]Hermes L, et al. Phase II Metabolism of Asarone Isomers In Vitro and in Humans Using HPLC-MS/MS and HPLC-qToF/MS. Foods. 2021 Aug 29;10 (9) :2032.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N15717/

Natural Products

No Development Reported