ESR2 Antilichaam - N-terminaal gebied: Biotine (ARP31652 P050-Biotine)

Estrogen receptor 2 (ER beta)

Erb, ESRB, ODG8, ESTRB, NR3A2, ER-BETA, ESR-BETA

2100

Q92731

NP_001428

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit, Sheep

The immunogen is a synthetic peptide directed towards the N terminal region of human ESR2

ESR2 is a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.

PLSCR1; MEOX2; NOTCH2NL; RFX6; MMS19; BCAS2; NCOA1; RPS18; MRPS15; MRPS22; ZC3HAV1; PTCD3; EXOSC4; MRPS2; MED4; MRPS27; MRPS31; MED17; TRIM24; NRIP1; NCOA3; STAU1; SP1; PABPC5; MYLK2; RPS11; RPS4X; RPLP0; RPL36AL; PPP5C; HSPA8; ESR2; ESR1; ACTB; SRA1; ARI

Biotin

Polyclonal Antibody

WB

Affinity Purified

There is BioGPS gene expression data showing that ESR2 is expressed in HepG2

0.5 mg/ml

Cow: 100%; Dog: 93%; Goat: 93%; Guinea Pig: 93%; Horse: 79%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 85%; Rat: 100%; Sheep: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

59kDa

Rothwarf, D.M., et al., (2006) J. Endocrinol. Invest. 29 (1), 5-10

Wet Ice

Directed towards isoforms 1-8.

530

ESR2

ESR2

Rabbit

Estrogen receptor beta

NM_001437

TPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGN