ESRRA Antibody - N-terminal regio : Biotine (ARP45617 P050-Biotin)

Estrogen-related receptor alpha

ERR1, ERRa, ESRL1, NR3B1, ERRalpha

2101

P11474

NP_004442

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Yeast

The immunogen is a synthetic peptide directed towards the N terminal region of human ESRRA

ESRRA is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes.The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

SUMO2; SUMO3; NSD1; NCOA1; EXOSC6; SMARCD3; ESR1; PIAS4; NXF1; ATXN1; MAP2K5; FUS; ADH5; WDR36; ZNF606; C2CD5; IPO13; TFAP4; Cebpb; ESRRG; PPARGC1A; MACF1; EIF3I; NR0B2; NRIP1; NCOA3; TNNI2; SRC; PROX1; DUT; NR0B1; UBC; PARK2; ZNF658B; SPICE1; KDM3B; DPF1

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Yeast: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

46kDa

Ao, A., (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (22), 7821-7826

Wet Ice

423

ESRRA

ESRRA

Rabbit

Steroid hormone receptor ERR1

NM_004451

KEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVN