ESRRB Antilichaam

ESRRB Antibody: The estrogen-related receptor beta (ESRRB) was initially identified in mouse embryonic carcinoma stem cells and was found to be expressed exclusively in trophoblast progenitor cells between days 6.5 and 7.5 post coitum. Recent studies have shown that ESRRB is part of an POU5F1/Oct4-centered protein interaction network in embryonic stem (ES) cells. It is thought to interact with other ES transcription factors such as NANOG within this network, activating POU5F1 transcription and thereby sustaining self-renewal and pluripotency in ES cells.

2103

O95718

NP_004443

Human

Unconjugated

Primary Antibodies

Stem Cell

ESRRB Antibody is affinity chromatography purified via peptide column.

Cat. No. 1301 - Human Heart Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Mouse: (89%), Rat: (89%)

ESRRB Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

ESRRB antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

ESRRB

Cat. No. 10-501 - Human Heart Tissue Slide

Estrogen-related receptor beta

Homo sapiens

Pettersson K, Svensson K, Mattsson R, et al. Expression of a novel member of estrogen response element-binding nuclear receptors is restricted to the early stages of chorion formation during mouse embryogenesis. Mech. Dev. 1996; 54:211-23.

Van den Berg DL, Snoek T, Mullin NP, et al. An Oct4-centered protein interaction network in embryonic stem cells. Cell Stem Cell 2010; 6:369-81.

Zhang X, Zhang J, Wang T, et al. Esrrb activates Oct4 transcription and sustains self-renewal and pluripotency in embryonic stem cells. J. Biol. Chem. 2008; 283:35825-33.

ESRRB Antibody: ERR2, ERRb, ESRL2, NR3B2, DFNB35, ERRB2, Steroid hormone receptor ERR2, ERR beta-2, ERR-beta

ELISA, WB, IHC-P, IF

238550159

Liquid