Estrogeen receptor-alfa (fosfo Tyr537) Antilichaam

Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

2099

P03372

NP_000116.2

Human, Mouse

Estrogen Receptor-alpha (phospho Tyr537) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 537 (P-L-Y (p) -D-L) derived from Human Estrogen Receptor-alpha.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

66 kDa

IgG

The antibody detects endogenous levels of ER-alpha only when phosphorylated at tyrosine 537.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

ESR1

Estrogen receptor 1

Homo sapiens

Sehime Temel, Endocrinology, Oct 2002; 143: 3974.

Xin-Tian Zhang, AACR Meeting Abstracts, Apr 2005; 2005: 302.

Suwit J. Somponpun, Am J Physiol Regulatory Integrative Comp Physiol, Sep 2004; 287: R661 - R669.

Marcello Maggiolini, Cancer Res., Oct 1999

ER, ESR, ESR1, ESTR, NR3A1

WB, IHC

62821794

Liquid