ETV6 Antilichaam

This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

2120

P41212

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ETV6 (NP_001978.1) .

Unconjugated

Primary Antibodies

Cancer, Transcription

Affinity purification

HepG2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 55kDa

IgG

WB: 1:500 - 1:2000

ETV6

Mouse lung

Mouse spleen

Rat testis

Ets variant 6

Homo sapiens

ETV6, TEL, TEL/ABL

WB

Liquid