EWSR1 Antilichaam - middengebied: Biotine (ARP40749_P050-Biotine)

Ewing sarcoma breakpoint region 1

EWS, EWS-FLI1, bK984G1.4

2130

Q01844

NP_005234

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human EWSR1

EWSR1 is a putative RNA binding protein. Mutations in this gene, specifically a t (11;22) (q24; q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in two products.This gene encodes a putative RNA binding protein. Mutations in this gene, specifically a t (11;22) (q24; q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in two products.

SSBP3; SEC24A; TFG; SEC24D; PEF1; MAPK1IP1L; ATPAF2; TRAF2; TRAF1; PLSCR1; PRR13; UBC; RPA3; RPA2; RPA1; EZH2; SUZ12; RNF2; BMI1; rev; ITCH; WBP4; PRMT1; CCDC7; YY1AP1; MRPS18B; UBD; CD81; RIOK2; NONO; ITGB5; ITGA4; FUS; FN1; EWSR1; EPAS1; EP300; HNRNPUL1

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

EWSR1 is strongly supported by BioGPS gene expression data to be expressed in HeLa EWSR1 is supported by BioGPS gene expression data to be expressed in HEK293

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

68kDa

Brandal, P., (2008) Genes Chromosomes Cancer 47 (7), 558-564

Wet Ice

656

EWSR1

EWSR1

Rabbit

RNA-binding protein EWS

NM_005243

QPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQS