EXD2 Polyklonale Antilichaam, AbBy FluorTM 488 Vervoeging

Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

Exonuclease 3'-5' domain-containing protein 2; EXD2; C14orf114; EXDL2

55218

Q9NVH0

Nucleus

Human, Mouse, Rat

351-621/621

EXD2

AbBy Fluor™ 488

KLH conjugated synthetic peptide derived from human EXD2

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

499nm/519nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

WB shows isoform 2

55218

Dog, Cow, Sheep, Pig, Horse