
EXOSC5 Polyklonale Antilichaam, Biotinevervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3 to 5 exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3 region. EXOSC5 (Exosome component 5), also known as Exosome complex exonuclease RRP46 and CML28 (Chronic myelogenous leukemia tumor antigen 28), is one of at least eleven components of the exosome complex and is required for processing of 7S pre-RNA to mature 5.8S rRNA. Located in the nucleus, EXOSC5 interacts with both EXOSC1 and EXOSC7. EXOSC5 is exclusively expressed in normal testis, though is found to be highly expressed in many hematopoietic and epithelial tumor cell lines, suggesting that it may be an appropriate target for antigen-specific immunotherapy.
Chronic myelogenous leukemia tumor antigen 28; CML28; EXOS5_HUMAN; EXOSC 5; Exosc5; Exosome complex component rrp46; exosome complex exonuclease RRP46; Exosome component 5; exosome component Rrp46; hRrp46p; p12B; Ribosomal RNA processing protein 46; Ribosomal RNA processing protein 46, S. cerevisiae, homolog of; Ribosomal RNA-processing protein 46; RRP41B; RRP46; Rrp46p.
56915
Q9NQT4
Nucleus
• Rabbit
Mouse
141-235/235
EXOSC5
• Polyclonal
• IgG
Biotin
KLH conjugated synthetic peptide derived from human EXOSC5
ELISA, IHC-P, IHC-F
Purified by Protein A.
1µg/µl
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C for 12 months.
56915
Human, Rat, Dog, Cow, Sheep, Pig, Horse
Beschrijving
EXOSC5 Polyklonale Antilichaam, Biotinevervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
Specificaties
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