EZH2 Antilichaam - N-terminalgebied: HRP (ARP38470 P050-HRP)

Enhancer of zeste homolog 2 (Drosophila)

WVS, ENX1, KMT6, WVS2, ENX-1, EZH2b, KMT6A

2146

Q15910

NP_004447.2

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human EZH2

EZH2 is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems.

FBXW11; CEP63; HOTAIR; EED; BRCA1; SUZ12; SNAI1; SRSF1; SDCBP; UPF1; RBBP7; RBBP4; RAP1GAP; PLEC; PKM; POTEE; DHX36; AEBP2; HIST4H4; KLC4; SERPINB12; PHF5A; FIP1L1; FBXL18; CPSF7; DDX3X; DBN1; SLC25A10; COPB1; CALML3; ATP5C1; ATP5B; ATP2A2; ARG1; AR; ANXA

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

Affinity Purified

EZH2 is supported by BioGPS gene expression data to be expressed in MCF7

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

85kDa

Mural, R.J., (2005) Direct Submission

Wet Ice

From peptide immunogen, will recognize all 5 isoforms.

751

EZH2

EZH2

Rabbit

Histone-lysine N-methyltransferase EZH2

NM_001203247

KGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQE