Ezrin (fosfo Tyr353) Antilichaam

Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

7430

P15311

NP_001104547.1

Human, Mouse

Ezrin (Phospho-Tyr353) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 353 (Q-D-Y (p) -E-E) derived from Human EZRIN.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

81 kDa

This antibody detects endogenous level of Ezrin only when phosphorylated at tyrosine 353.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

EZR

Ezrin

Homo sapiens

Zhao H, et al. (2004) Proc Natl Acad Sci U S A101 (25) : 9485-9490. Wang Q, et al. (2003) J Biol Chem 278 (48) : 47731-47743. Gautreau A, et al. (1999) Proc Natl Acad Sci U S A 96 (13) : 7300-7305. Crepaldi T, et al. (1997) J Cell Biol 138 (2) : 423-34.

CVL, CVIL, VIL2, HEL-S-105, ESR, NR3A1, Cytovillin, EZRI, Villin 2, p81

WB, IHC

161702986

Liquid