F2 Antilichaam

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants.

2147

P00734

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 75-280 of human F2 (NP_000497.1) .

Unconjugated

Primary Antibodies

Apoptosis, Cell Cycle

Affinity purification

Raji

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 88kDa

IgG

F2

Mouse heart

Rat kidney

Coagulation factor II (thrombin)

Homo sapiens

F2, PT, THPH1, RPRGL2

WB, IF

Liquid