F2 Antilichaam - middengebied: Biotine (ARP41757 P050-Biotine)

Coagulation factor II (thrombin)

PT, THPH1, RPRGL2

2147

P00734

NP_000497

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human F2

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life.Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

ST13; FN1; DDIT3; ALB; F11; PROZ; ITGA2B; SERPING1; HGFAC; AKR7A2; CPB2; F2RL3; F2RL2; SERPINA5; SERPINB8; AANAT; F2RL1; F9; F8; GP1BA; KNG1; F5; C6; PLAU; THBS1; THBD; F2R; SERPINE2; F2; PROS1; AMBP; PROC; GP5; SERPINE1; SERPINB6; SPP1; IGFBP5; IGFBP3; S

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Cow: 92%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Sheep: 93%; Zebrafish: 77%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

70kDa

Rossi, E., (2008) Thromb. Haemost. 99 (6), 1030-1034

Wet Ice

622

F2

F2

Rabbit

Prothrombin

NM_000506

ISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLE