F5 Antilichaam

This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance.

2153

P12259

Human

Recombinant fusion protein containing a sequence corresponding to amino acids 300-510 of human F5 (NP_000121.2) .

Unconjugated

Primary Antibodies

Other

Affinity purification

Human plasma

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 310kDa

IgG

WB: 1:500 - 1:2000

F5

Human platelet

Coagulation factor V

Homo sapiens

FVL, PCCF, RPRGL1, THPH2, coagulation factor V, activated protein c cofactor, coagulation factor V (proaccelerin, labile factor), coagulation factor V jinjiang A2 domain, factor V Leiden

WB

Liquid