Factor IX (F9) (NM 000133) Humaan Recombinant eiwit
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Sep 2015]
Purified recombinant protein of Human coagulation factor IX (F9), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
F9 p22; FIX; HEMB; P19; PTC; THPH8
2158
P00740
NM_000133
Xq27.1
E. coli
N-GST and C-His
Complement and coagulation cascades
Complement and coagulation cascades
>50 ug/mL as determined by microplate BCA method
> 80% as determined by SDS-PAGE and Coomassie blue staining
Liquid
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
Druggable Genome, Protease, Secreted Protein
79.8 kDa
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
F9
Human
NP_000124
https://www.ncbi.nlm.nih.gov/gene/2158
https://www.uniprot.org/uniprot/P00740
https://www.ncbi.nlm.nih.gov/nuccore/NM_000133
https://www.ncbi.nlm.nih.gov/nuccore/NP_000124
Beschrijving
Factor IX (F9) (NM 000133) Humaan Recombinant eiwit Beschikbaar in 50 µg. Bestel eenvoudig online met snelle levering.
Specificaties
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