Factor IX Polyklonale Antilichaam, Cy3 Vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (prothrombin, and factors X, IX, V, and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble fibrin clots and the promotion of platelet aggregation (1-3) . Coagulation factor IX (plasma thromboplastic component, F9, F.IX, HEMB) is a vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor (3,4) . Factor XIa mediated proteolytic cleavage of factor IX generates factor IXa, an active serine protease composed of a 145 amino acid light chain and a 236 amino acid catalytic heavy chain, linked through disulfide bonds (5) . Genetic alterations at the Factor IX locus such as point mutations, insertions and deletions, can lead to hemophilia B, also known as Christmas disease (6) .
Christmas Disease; Christmas factor; Coagulant factor IX; Coagulation factor 9; Coagulation factor IX plasma thromboplastic component; Coagulation factor IX; Coagulation factor IXa heavy chain; F9; FA9_HUMAN; Factor 9; Factor IX Deficiency; Factor9; FactorIX; FIX; GLA domain; Haemophilia B; MGC129641; MGC129642; P19 antibody Plasma thromboplastic component; Plasma thromboplastin component; PTC; Truncated coagulation factor IX.
2158
• Rabbit
Human, Mouse, Rat
381-461/461
Factor IX
• Polyclonal
• IgG
Cy3
KLH conjugated synthetic peptide derived from human Coagulation factor IXa heavy chain
WB, IF
Purified by Protein A.
512,550nm/570,615nm
1µg/µl
WB (1:300-5000), IF ()
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
2158
Beschrijving
Factor IX Polyklonale Antilichaam, Cy3 Vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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