FADD Antilichaam - C-terminalgebied: Biotine (ARP30294_P050-Biotine)

Fas (TNFRSF6) -associated via death domain

Mort1/F, Mort1/FADD

14082

Q61160

NP_034305

Mouse

The immunogen is a synthetic peptide directed towards the C terminal region of mouse FADD

Fadd is apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.

Atg16l1; Atg7; Atg12; Map1lc3a; Ripk1; Casp8; Atg5; Fas; Pidd1; Cflar; Tnf; Nol3

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Mouse: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

23kDa

Wet Ice

205

FADD

FADD

Rabbit

Protein FADD

NM_010175

ASVAGLVKALRTCRLNLVADLVEEAQESVSKSENMSPVLRDSTVSSSETP