FAK Antilichaam

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.

5747

Q05397

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 425-660 of human FAK (NP_005598.3) .

Unconjugated

Primary Antibodies

Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction

Affinity purification

U-87MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 119kDa

IgG

WB: 1:1000 - 1:2000

PTK2

BT-474

Mouse brain

Mouse lung

Mouse liver

Rat brain

Protein tyrosine kinase 2

Homo sapiens

PTK2, FADK, Fadk1, Focal adhesion kinase, FRNK, FADK 1, Focal adhesion kinase 1, FAK1, p125FAK, PPP1R71, Protein-tyrosine kinase 2, PTK2 protein tyrosine kinase 2, FAK, pp125 FA kinase, Pp125FAK

WB

Liquid