FAM212A Antilichaam

FAM212A, initially identified as INCA (induced in neural crest by AP-2alpha) in xenopus, is expressed primarily in neural crest cells and their derivatives (1) . FAM212A can associate with the P21-kinase protein PAK4 and this association modulates cytoskeletal dynamics (1) . In mammals, FAM212A is thought to play a role in neural tube closure; a significant fraction of FAM212A-null mice exhibited exencephaly (2) .

389119

Q96EL1

NP_976248

Human, Mouse

Unconjugated

Primary Antibodies

Stem Cell, Neuroscience

FAM212A antibody is affinity chromatography purified via peptide column.

Cat. No. 1287 - EL4 Cell Lysate

1 mg/mL

FAM212A antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

FAM212A antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

FAM212A antibody is human and mouse . At least two isoforms of FAM212A are known to exist; this antibody will recognize both isoforms.

FAM212A

Family with sequence similarity 212 member A

Homo sapiens

Luo T, Xu Y, Hoffman TL, et al. Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development. Dev. 2007; 134:1279-89.

Reid BS, Sargent TD, and Willams T. Generation and characterization of a novel neural crest marker allele, Inka1-LacZ, reveals a role for Inka1 in mouse neural tube closure. Dev. Dyn. 2010; 239:1188-96.

Family with sequence similarity 212 member A, INKA1, C3orf54

ELISA, WB

42766424

Liquid