FAM59B Antilichaam

FAM59B Antibody: FAM59B is related to the FAM59A protein (also known as GAREM) . While little is known of the role of the FAM59B protein, FAM59A is a downstream molecule in the EGF signaling pathway and binds Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. Like FAM59A, FAM59B may play a role in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells.

150946

Q75VX8

Q75VX8

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Signal Transduction

FAM59B Antibody is affinity chromatography purified via peptide column.

Cat. No. 1220 - SK-N-SH Cell Lysate

1 mg/mL

FAM59B Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

FAM59B antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

FAM59B

Cat. No. 10-301 - Human Brain Tissue Slide

Family with sequence similarity 59, member B

Homo sapiens

Blagoev B, Ong SE, Kratchmarova I, et al. Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics. Nat. Biotechnol.2004; 22:1139-45.

Tashiro K, Tsunematsu T, Okubo H, et al. GAREM, a novel adaptor protein for growth factor receptor-bound protein 2, contributes to cellular transformation through activation of extracellular signal-regulated kinase signaling. J. Biol. Chem.2009; 284:20206-14.

FAM59B Antibody: FAM59B, FAM59B, KIAA2038, HRIHFB2063, GRB2-associated and regulator of MAPK protein-like, GRB2-associated and regulator of MAPK1-like

ELISA, WB, IHC-P, IF

190359325

Liquid